Drugs / 90Y-BC8-DOTA
last change Jul 2020 re-read 2 minutes ago

90Y-BC8-DOTA

also known as 90Y-BC8 Ab

Monoclonal antibody

Developed for
Hodgkins lymphoma · mantle cell lymphoma · plasma cell myeloma · T-cell non-Hodgkin lymphoma
Investigated by
Fred Hutchinson Cancer Center · National Cancer Institute (NCI)

Trials 2 · a red edge is where a trial was stopped

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01503242 Jan 2012 → Jun 2017 plasma cell myeloma Fred Hutchinson Cancer Center Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01921387 Oct 2013 → Jul 2017 Hodgkins lymphoma, T-cell non-Hodgkin lymphoma, mantle cell lymphoma Fred Hutchinson Cancer Center Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as 90Y-BC8-DOTA “A Phase I Study of 90Y-BC8-DOTA Monoclonal Antibody, Fludarabine and TBI Followed by HLA-Matched, Allogeneic Peripheral Blood Stem Cell Transplant for the Treatment of Multiple Myeloma” NCT01503242
1

90Y-BC8-DOTA (yttrium Y 90 anti-CD45 monoclonal antibody BC8)” NCT01921387

Known as 90Y-BC8 Ab “OUTLINE: This is a dose-escalation study of yttrium Y 90 anti-CD45 monoclonal antibody BC8 (90Y-BC8 Ab).” NCT01503242
Modality Monoclonal antibody “90Y-BC8-DOTA Monoclonal AntibodyNCT01503242
Route Intravenous “Patients receive 90Y-BC8 Ab intravenously (IV) on day -12” NCT01503242