Drugs / Chlorprothixene
Chlorprothixene
also known as
CHLORPROTHIXENE HYDROCHLORIDE · Clorprotixeno · N-714 · N-714RO 4-0403 · NSC-18720 · RO 4-0403 · Taractan · Truxal
Small molecule targets DRD2, DRD3, HTR2A, HTR2C via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | TARACTAN | — | 1962-03-23 | fda.gov ↗ |
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Chlorprothixene | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02374567 ↗ |
| Known as | CHLORPROTHIXENE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | Clorprotixeno | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | N-714 | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | N-714RO 4-0403 | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | NSC-18720 | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | RO 4-0403 | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | Taractan | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Known as | Truxal | ChEMBL registry synonym — accepted as the source's own label CHEMBL908 ↗ |
| Action | Inhibit | “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL908 ↗3“Serotonin 2c (5-HT2c) receptor antagonist” CHEMBL908 ↗ “Dopamine D3 receptor antagonist” CHEMBL908 ↗ “Dopamine D2 receptor antagonist” CHEMBL908 ↗ |
| Modality | Small molecule | — CHEMBL908 ↗ |
| Target | DRD2 | “Dopamine D2 receptor antagonist” CHEMBL908 ↗ |
| Target | DRD3 | “Dopamine D3 receptor antagonist” CHEMBL908 ↗ |
| Target | HTR2A | “Serotonin 2a (5-HT2a) receptor antagonist” CHEMBL908 ↗ |
| Target | HTR2C | “Serotonin 2c (5-HT2c) receptor antagonist” CHEMBL908 ↗ |