Drugs / Rocklatan
last change Jan 2026 re-read 2 minutes ago

Rocklatan

also known as PG324

Other / unclassified

Developed for
glaucoma · ocular hypertension · open-angle glaucoma
Investigated by
Aerie Pharmaceuticals · Alcon Research · Oregon Health and Science University

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) ROCKLATAN 2019-03-12 fda.gov

Trials 2 · a red edge is where a trial was stopped

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 31 trial
Phase 3 NCT02674854 Feb 2016 → Mar 2017 ocular hypertension, open-angle glaucoma Aerie Pharmaceuticals Completed No outcome recorded
Phase 41 trial
Phase 4 NCT07174401 Jan → Dec 2026 expected glaucoma Oregon Health and Science University Not yet recruiting No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT07048886 Comparator Jul 2025 → Dec 2026 expected open-angle glaucoma Center for Sight Las Vegas Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Rocklatan ClinicalTrials.gov intervention name — accepted as the source's own label NCT07174401
1

NCT07048886

Known as PG324 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02674854
Action Inhibit “a Rho kinase inhibitor” NCT07048886
Modality Other / unclassified “a fixed dose combination of a Rho kinase inhibitor and a prostaglandin analogue” NCT07048886
Route Other “Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months.” NCT07174401