Drugs / Tregalizumab
last change Jan 2022 re-read 3 minutes ago

Tregalizumab

Monoclonal antibody targets CD4 via inhibition

Developed for
allergic asthma · rheumatoid arthritis
Investigated by
AbbVie · Biotest · T-Balance Therapeutics GmbH

Trials 2

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04673591 Dec 2020 → Jan 2022 allergic asthma, house allergic alveolitis T-Balance Therapeutics GmbH Completed No outcome recorded
Phase 2 NCT01999192 Oct 2013 → Jul 2015 rheumatoid arthritis Biotest Terminated Missed primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Tregalizumab ClinicalTrials.gov intervention name — accepted as the source's own label NCT04673591 ↗
1

NCT01999192 ↗

Action Inhibit “Biological activity was shown by dose-dependent CD4 downmodulation.” PMID 29343509 ↗ Jan 2018
Modality Monoclonal antibody “humanized anti-CD4 mAb” NCT01999192 ↗
Route Subcutaneous “25mg Tregalizumab s.c. weekly” NCT01999192 ↗
Target CD4 “Biological activity was shown by dose-dependent CD4 downmodulation.” PMID 29343509 ↗ Jan 2018