Drugs / RADOTERMIN
RADOTERMIN
also known as
rhGDF-5 · recombinant human growth and differentiation factor-5 · MP52 · Radotermina · Radotermine
Trials 4
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT01182337 | Jun 2010 → Jun 2014 | lumbar disk degenerative disorder | DePuy Spine | Completed | No outcome recorded |
| Phase 1/2 | NCT01158924 | Mar 2010 → Mar 2014 | lumbar disk degenerative disorder | DePuy Spine | Completed | No outcome recorded |
| Phase 1/2 | NCT00813813 | Jun 2008 → Jun 2013 | intervertebral disk degenerative disorder | DePuy Spine | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT01124006 | Jan 2010 → Sep 2014 | intervertebral disk degenerative disorder | DePuy Spine | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | RADOTERMIN | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108637 ↗ |
| Known as | MP52 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108637 ↗ |
| Known as | Radotermina | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108637 ↗ |
| Known as | Radotermine | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108637 ↗ |
| Known as | recombinant human growth and differentiation factor-5 | “The API is recombinant human growth and differentiation factor-5 (rhGDF-5), a recombinant version of human GDF-5.” NCT01182337 ↗2“The API is recombinant human growth and differentiation factor-5 (rhGDF-5), a recombinant version of human GDF-5.” NCT01158924 ↗ “The API is recombinant human growth and differentiation factor-5 (rhGDF-5), a recombinant version of human GDF-5.” NCT01124006 ↗ |
| Known as | rhGDF-5 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00813813 ↗ |
| Action | Activate | “In vitro experiments have shown that rhGDF-5 can stimulate gene expression and synthesis of the extracellular matrix proteins type II collagen and aggrecan.” NCT01158924 ↗ |
| Modality | Protein / enzyme biologic | “The API is recombinant human growth and differentiation factor-5 (rhGDF-5), a recombinant version of human GDF-5.” NCT00813813 ↗ |
| Route | Other | “intradiscal injections of rhGDF-5” NCT00813813 ↗ |