Drugs / Eltrekibart
last change Aug 2026 re-read 2 minutes ago

Eltrekibart

also known as LY3041658

Monoclonal antibody

Developed for
hidradenitis suppurativa · ulcerative colitis
Investigated by
Eli Lilly and Company

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT07545590 Apr → Aug 2026 overdue Eli Lilly and Company Recruiting No outcome recorded
Phase 1 NCT04653168 Dec 2020 → May 2021 Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT02896868 Nov 2016 → Mar 2019 psoriasis Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT02148627 Jun 2014 → Feb 2017 Eli Lilly and Company Completed No outcome recorded
Phase 23 trials
Phase 2 NCT06598943 Oct 2024 → Dec 2027 expected ulcerative colitis Eli Lilly and Company Recruiting No outcome recorded
Phase 2 NCT06046729 Oct 2023 → Sep 2025 overdue hidradenitis suppurativa Eli Lilly and Company Active not recruiting No outcome recorded
Phase 2 NCT04493502 Aug 2020 → Mar 2022 hidradenitis suppurativa Eli Lilly and Company Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as eltrekibart “A randomized, double-blind, placebo-controlled phase 2 study of eltrekibart, a novel septa-specific monoclonal antibody to CXCR1/2 ligands, in adults with hidradenitis suppurativa.” PMID 41061970 Oct 2025
2

NCT06046729

NCT06598943

Known as LY3041658 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04653168
4

NCT02148627

NCT04493502

NCT07545590

NCT02896868

Action Inhibit “Neutralizing CXC motif chemokine receptors 1 and 2 ligands offer a promising HS treatment strategy.” PMID 41061970 Oct 2025
Modality Monoclonal antibody “a novel septa-specific monoclonal antibody to CXCR1/2 ligands” PMID 41061970 Oct 2025
Route Subcutaneous “Administered SC” NCT02148627