Drugs / ergotamine
ergotamine
also known as
Cafergot · Ergomar · Ergostat · Ergotamina · Ergotamine bitartrate · Ergotamine d-tartrate · ERGOTAMINE TARTRATE · Ergotamine tartrate component of cafergot · +12 more
Small molecule targets HTR1D via activation
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | CAFERGOT | — | 1948-11-26 | fda.gov ↗ |
Trials 1 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT00223691 | Mar 2002 → Jan 2017 | autonomic nervous system disorder, orthostatic hypotension | Vanderbilt University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT01408069 Comparator | — | — | EMS | Withdrawn | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT01476930 Comparator | Jun 2008 → Sep 2009 | migraine disorder | Birjand University of Medical Sciences | Completed | No outcome recorded |
Evidence & citations 25 cited values
Every value below carries the sentence it was read from. 4 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ergotamine | “1 to 2 tablets ergotamine 1mg + caffeine 100mg + acetylsalicylic 350 mg + homatropine 1,2 mg” NCT01408069 ↗ |
| Known as | Cafergot | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergomar | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergostat | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamina | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamine bitartrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamine d-tartrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | ERGOTAMINE TARTRATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamine tartrate component of cafergot | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamine tartrate component of migergot | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamine tartrate component of wigraine | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Ergotamini tartras | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Femergin | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Gotamine tartrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Gynergen | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Lingraine | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Medihaler ergotamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Migril | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | NSC-41869 | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | NSC-95090 | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Known as | Wigrettes | ChEMBL registry synonym — accepted as the source's own label CHEMBL442 ↗ |
| Action | Activate | “Serotonin 1d (5-HT1d) receptor agonist” CHEMBL442 ↗ |
| Modality | Small molecule | — CHEMBL442 ↗ |
| Route | Oral | “Ergotamine: 1.0 mg PO. Single dose.” NCT00223691 ↗ |
| Target | HTR1D | “Serotonin 1d (5-HT1d) receptor agonist” CHEMBL442 ↗ |