Drugs / Cobiprostone
last change Jul 2016 re-read 3 minutes ago

Cobiprostone

also known as Cobiprostona · RU-8811 · SPI-8811

Small molecule targets CLCN2 via activation

Developed for
gastroduodenitis · mucositis · portal hypertension
Investigated by
Sucampo Pharma Americas, LLC · Sucampo Pharmaceuticals, Inc.

Trials 3

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02542215 Jun 2015 → Jul 2016 mucositis Sucampo Pharma Americas, LLC Terminated No outcome recorded
Phase 2 NCT00737594 Jul 2008 → Feb 2009 portal hypertension Sucampo Pharma Americas, LLC Terminated No outcome recorded Stop: Enrollment
Phase 2 NCT00597818 Aug 2007 → Apr 2009 gastroduodenitis, osteoarthritis, rheumatoid arthritis Sucampo Pharma Americas, LLC Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Cobiprostone ClinicalTrials.gov intervention name — accepted as the source's own label NCT00597818 ↗
2

NCT00737594 ↗

NCT02542215 ↗

Known as Cobiprostona ChEMBL registry synonym — accepted as the source's own label CHEMBL2103799 ↗
Known as RU-8811 ChEMBL registry synonym — accepted as the source's own label CHEMBL2103799 ↗
Known as SPI-8811 ChEMBL registry synonym — accepted as the source's own label CHEMBL2103799 ↗
Action Activate “Chloride channel protein 2 activator” CHEMBL2103799 ↗
Modality Small molecule — CHEMBL2103799 ↗
Route Oral “18 mcg cobiprostone capsules for oral administration” NCT00597818 ↗
Target CLCN2 “Chloride channel protein 2 activator” CHEMBL2103799 ↗