Drugs / GFB-887
last change Nov 2022 re-read 3 minutes ago

GFB-887

Small molecule targets TRPC5 via inhibition

Developed for
focal segmental glomerulosclerosis · diabetic kidney disease · minimal change disease
Investigated by
Goldfinch Bio, Inc.

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03970122 May 2019 → Mar 2020 — Goldfinch Bio, Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT04950114 Jul 2021 → Nov 2022 focal segmental glomerulosclerosis, glomerulonephritis, nephrosis Goldfinch Bio, Inc. Terminated No outcome recorded Stop: Business
Phase 2 NCT04387448 Jul 2020 → Nov 2022 diabetes mellitus, diabetic kidney disease, focal segmental glomerulosclerosis, minimal change disease +1 Goldfinch Bio, Inc. Terminated No outcome recorded Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as GFB-887 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04950114 ↗
2

NCT03970122 ↗

NCT04387448 ↗

Action Inhibit “GFB-887, a TRPC5 Channel Inhibitor” NCT03970122 ↗
Modality Small molecule “GFB-887 is a potent, small molecule inhibitor of TRPC5.” NCT04950114 ↗
Target TRPC5 “GFB-887, a TRPC5 Channel Inhibitor” NCT03970122 ↗