Drugs / DEPATUXIZUMAB
last change Aug 2020 re-read 2 minutes ago

DEPATUXIZUMAB

Monoclonal antibody targets EGFR

Developed for
cancer · adenocarcinoma
Investigated by
AbbVie · AbbVie · University of Chicago

Trials 4 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT01406119 Oct 2011 → Jan 2017 cancer AbbVie Completed No outcome recorded
Phase 1 NCT01472003 Oct 2011 → Dec 2012 cancer AbbVie Completed No outcome recorded
Phase 1 NCT01255657 Nov 2010 → Nov 2012 cancer AbbVie Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02213289 Jan 2015 → Feb 2020 adenocarcinoma University of Chicago Completed No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2019-05-17 AbbVie AbbVie Provides Update on Depatuxizumab Mafodotin (Depatux-M), an Investigational Medicine for Newly Diagnosed Glioblastoma, an Aggressive Form of Brain Cancer abbvie.com

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as DEPATUXIZUMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL3707294
Known as ABT-806 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01406119
3

NCT02213289

NCT01472003

NCT01255657

Known as Anti-egfr mab abt-806 ChEMBL registry synonym — accepted as the source's own label CHEMBL3707294
Known as Anti-egfr moab abt-806 ChEMBL registry synonym — accepted as the source's own label CHEMBL3707294
Modality Monoclonal antibody “Population Pharmacokinetics of ABT-806, an Investigational Anti-Epidermal Growth Factor Receptor (EGFR) Monoclonal AntibodyPMID 25761639 Oct 2015
Route Intravenous “following intravenous infusion of ABT-806” PMID 25761639 Oct 2015
Target EGFR “specific for a unique epitope of human epidermal growth factor receptor (EGFR)” PMID 25761639 Oct 2015