Drugs / Sudapyridine
last change Jun 2026 re-read 2 minutes ago

Sudapyridine

also known as WX-081 · 21l

Small molecule

Developed for
rifampicin-resistant tuberculosis · multidrug-resistant tuberculosis · pulmonary tuberculosis
Investigated by
Shanghai Jiatan Pharmatech Co., Ltd

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT06701136 May → Oct 2025 overdue rifampicin-resistant tuberculosis Shanghai Jiatan Pharmatech Co., Ltd Not yet recruiting No outcome recorded
Phase 1 NCT06701110 Sep 2024 → Dec 2025 overdue tuberculosis Shanghai Jiatan Pharmatech Co., Ltd Recruiting No outcome recorded
Phase 1 NCT06117514 Feb 2019 → Jul 2020 Shanghai Jiatan Pharmatech Co., Ltd Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04608955 Oct 2020 → Apr 2022 pulmonary tuberculosis Shanghai Jiatan Pharmatech Co., Ltd Completed No outcome recorded
Phase 31 trial
Phase 3 NCT05824871 Sep 2022 → Dec 2025 overdue multidrug-resistant tuberculosis, rifampicin-resistant tuberculosis Shanghai Jiatan Pharmatech Co., Ltd Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as sudapyridine “Based on bedaquiline, we describe herein discovery and development of a novel diarylpyridine series, which led to identification of WX-081 (sudapyridine, 21l).” PMID 35636648 May 2022
3

NCT06117514

NCT06701136

NCT05824871

Known as 21l “Based on bedaquiline, we describe herein discovery and development of a novel diarylpyridine series, which led to identification of WX-081 (sudapyridine, 21l).” PMID 35636648 May 2022
Known as WX-081 “In Study A, Cycle 1 (D1-D10): Participants will take Sudapyridine (WX-081) 300 mg once daily after breakfast.” NCT06701136
3

“Sudapyridine (WX-081)” NCT06117514

NCT04608955

NCT06701110

Modality Small molecule “Based on bedaquiline, we describe herein discovery and development of a novel diarylpyridine series, which led to identification of WX-081 (sudapyridine, 21l).” PMID 35636648 May 2022
1

CHEMBL5314931

Route Oral “Participants with newly-treated drug sensitivity tuberculosis receive WX-081 150mg orally once daily for 2 weeks.” NCT04608955