Drugs / recombinant Escherichia coli-asparaginase
last change May 2018 re-read 2 minutes ago

recombinant Escherichia coli-asparaginase

Developed for
acute lymphoblastic leukemia
Investigated by
medac GmbH

Trials 1 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT00784017 Oct 2008 → Oct 2012 acute lymphoblastic leukemia medac GmbH Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as recombinant Escherichia coli-asparaginase “The efficacy and safety of recombinant Escherichia coli-asparaginase (rASNase) was compared to native E.coli asparaginase (Asparaginase medac).” PMID 29727043 May 2018
Known as rASNase “This multicentric phase III study is designed to assess the efficacy and safety of recombinant asparaginase (rASNase) in comparison to Asparaginase medac™ during treatment of...” NCT00784017
Known as recombinant asparaginase “This multicentric phase III study is designed to assess the efficacy and safety of recombinant asparaginase (rASNase) in comparison to Asparaginase medac™ during treatment of...” NCT00784017
Known as recombinant E. coli asparaginase “Efficacy and safety of recombinant E. coli asparaginase in children with previously untreated acute lymphoblastic leukemia: A randomized multicenter study of the Dutch...” PMID 29727043 May 2018
Route Intravenous “5.000U /m²; IV; day 12, 15, 18, 21, 24, 27, 30, 33” NCT00784017