Drugs / Anti-thymocyte globulin (ATG)
last change Mar 2026 re-read 3 minutes ago

Anti-thymocyte globulin (ATG)

Protein / enzyme biologic

Developed for
leukemia · lymphoma
Investigated by
M.D. Anderson Cancer Center · St. Jude Children's Research Hospital

Trials 2

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00972101 Sep 2009 → Sep 2011 disease related to hematopoietic stem cell transplant, leukemia, lymphoma M.D. Anderson Cancer Center Withdrawn No outcome recorded Stop: Enrollment
Phase 21 trial
Phase 2 NCT05579769 Mar 2023 → May 2024 myeloid neoplasm St. Jude Children's Research Hospital Terminated No outcome recorded
Comparator or background therapy6 trials
Phase 1/2 NCT07061574 Comparator Mar 2026 → Apr 2030 expected type 1 diabetes mellitus City of Hope Medical Center Recruiting No outcome recorded
Phase 2 NCT03734601 Background Nov 2018 → Dec 2019 Hodgkins lymphoma, T-cell non-Hodgkin lymphoma, acute myeloid leukemia, chronic lymphocytic leukemia/small lymphocytic lymphoma +2 Stanford University Completed No outcome recorded
Phase 2 NCT01359254 Background Apr 2010 → Sep 2011 hematologic disorder University of Chicago Terminated No outcome recorded Stop: Enrollment
Phase 2 NCT00720629 Comparator Dec 2007 → Dec 2013 graft versus host disease H. Lee Moffitt Cancer Center and Research Institute Terminated No outcome recorded
Phase 2 NCT00176865 Comparator Aug 2002 → Aug 2012 Chediak-Higashi syndrome, Griscelli syndrome, Langerhans cell histiocytosis, X-linked lymphoproliferative syndrome Masonic Cancer Center, University of Minnesota Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Anti-thymocyte globulin (ATG) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00568633 ↗
7

NCT00972101 ↗

NCT03734601 ↗

NCT00176865 ↗

NCT07061574 ↗

NCT00720629 ↗

NCT05579769 ↗

NCT01359254 ↗

Modality Protein / enzyme biologic “ATG (brand name Thymoglobulin) a polyclonal T cell antibody preparation.” NCT07061574 ↗
Route Intravenous “30 mg/kg IV Day -5 through Day -1” NCT00176865 ↗