Drugs / BI 44370
last change Jun 2009 re-read 2 minutes ago

BI 44370

also known as BI 44370 TA · BI 44370 BS · J3.353.239C

Small molecule targets CALCRL via inhibition

Developed for
migraine disorder
Investigated by
Boehringer Ingelheim

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 17 trials
Phase 1 NCT02215759 Jan → Jun 2009 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT00743015 Sep 2008 → Mar 2009 migraine disorder Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02215772 Sep → Oct 2008 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02215031 Sep → Nov 2008 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02217514 Feb → Mar 2008 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02215746 Jan → Apr 2008 Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02215018 Apr → Aug 2007 Boehringer Ingelheim Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00751803 Aug 2008 → May 2009 migraine disorder Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as BI 44370 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02215746
3

NCT02217514

NCT02215031

NCT00743015

Known as BI 44370 BS ClinicalTrials.gov intervention name — accepted as the source's own label NCT02215772
Known as BI 44370 TA ClinicalTrials.gov intervention name — accepted as the source's own label NCT02215759
2

NCT02215018

NCT00751803

Known as J3.353.239C ChEMBL registry synonym — accepted as the source's own label CHEMBL3334624
Action Inhibit “Calcitonin gene-related peptide type 1 receptor antagonist” CHEMBL3334624
Modality Small molecule CHEMBL3334624
Route Oral “Relative Bioavailability Following Single Oral Administration of 200 mg of BI 44370 During and Between Migraine Attacks in Male and Female Migraine Patients. An Open-label,...” NCT00743015
Target CALCRL “Calcitonin gene-related peptide type 1 receptor antagonist” CHEMBL3334624