Drugs / ENBEZOTINIB
last change May 2023 re-read 3 minutes ago

ENBEZOTINIB

also known as TPX-0046

Small molecule targets RET, SRC via inhibition

Developed for
medullary thyroid gland carcinoma · metastatic neoplasm · non-small cell lung carcinoma
Investigated by
Turning Point Therapeutics, Inc.

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT04161391 Dec 2019 → May 2023 medullary thyroid gland carcinoma, metastatic neoplasm, non-small cell lung carcinoma Turning Point Therapeutics, Inc. Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ENBEZOTINIB ChEMBL registry synonym — accepted as the source's own label CHEMBL5095062 ↗
Known as TPX-0046 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04161391 ↗
Action Inhibit “RET/SRC inhibitor” NCT04161391 ↗
Modality Small molecule — CHEMBL5095062 ↗
Route Oral “Oral TPX-0046 capsules” NCT04161391 ↗
Target RET “RET/SRC inhibitor” NCT04161391 ↗
Target SRC “RET/SRC inhibitor” NCT04161391 ↗