Drugs / bivatuzumab mertansine
last change Feb 2005 re-read 3 minutes ago

bivatuzumab mertansine

also known as BIWA-1-DM1 · Biwa-4 mertansine

targets CD44

Developed for
breast neoplasm · head and neck neoplasm · squamous cell carcinoma
Investigated by
Boehringer Ingelheim

Trials 4

20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02254044 Oct 2003 → Nov 2004 squamous cell carcinoma Boehringer Ingelheim Terminated No outcome recorded
Phase 1 NCT02254031 Jul 2003 → Jan 2005 breast neoplasm Boehringer Ingelheim Terminated No outcome recorded
Phase 1 NCT02254005 Oct 2002 → Dec 2004 breast neoplasm Boehringer Ingelheim Completed No outcome recorded
Phase 1 NCT02254018 Sep 2002 → Feb 2005 head and neck neoplasm Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as bivatuzumab mertansine ClinicalTrials.gov intervention name — accepted as the source's own label NCT02254005 ↗
3

NCT02254031 ↗

NCT02254044 ↗

NCT02254018 ↗

Known as BIWA-1-DM1 ChEMBL registry synonym — accepted as the source's own label CHEMBL2109288 ↗
Known as Biwa-4 mertansine ChEMBL registry synonym — accepted as the source's own label CHEMBL2109288 ↗
Route Intravenous “Administered intravenously” NCT02254005 ↗
Target CD44 “CD44 antigen binding agent” CHEMBL2109288 ↗