Drugs / GSK933776
last change Apr 2016 re-read 3 minutes ago

GSK933776

Monoclonal antibody targets APP

Developed for
Alzheimer disease
Investigated by
GlaxoSmithKline · Quintiles, Inc.

Trials 4

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02033668 Jan → Jul 2014 — GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT01424436 May 2010 → Dec 2011 Alzheimer disease GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00459550 Mar 2007 → May 2011 Alzheimer disease GlaxoSmithKline Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01342926 Jun 2011 → Apr 2016 — GlaxoSmithKline Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as GSK933776 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01424436 ↗
3

NCT01342926 ↗

NCT00459550 ↗

NCT02033668 ↗

Modality Monoclonal antibody “Fc-inactivated anti-β amyloid (Aβ) monoclonal antibody (mAb) GSK933776” PMID 25789616 ↗ Mar 2015
Route Intravenous “intravenous GSK933776 0.001-6 mg/kg” PMID 25789616 ↗ Mar 2015
Target APP “Amyloid-beta A4 protein binding agent” CHEMBL2109300 ↗