Drugs / Huaier Granule
Huaier Granule
Trials 23
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT07413354 | Apr 2026 → Mar 2027 expected | hepatocellular carcinoma | Tongji Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT05673824 | Jan 2023 → Sep 2025 | poisoning | Fudan University | Completed | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT04291053 | Apr → Aug 2020 | COVID-19 | Tongji Hospital | Unknown | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT07197853 | Oct 2025 → Jun 2028 expected | non-small cell lung carcinoma | Xin Ye | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT02785146 | Jun 2016 → Jan 2018 | colorectal cancer | Sixth Affiliated Hospital, Sun Yat-sen University | Unknown | No outcome recorded |
| Phase 3 | NCT02796820 | Jun 2016 → Jan 2018 | colorectal cancer | Sixth Affiliated Hospital, Sun Yat-sen University | Unknown | No outcome recorded |
| Phase 414 trials · 1 met primary | ||||||
| Phase 4 | NCT07358520 | Jan 2026 → Jan 2027 expected | proteinuria | Fudan University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT05871437 | Sep 2025 → Jan 2026 overdue | breast cancer | Fudan University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06090994 | Oct 2024 → Jul 2027 expected | colorectal cancer | Fudan University | Recruiting | No outcome recorded |
| Phase 4 | NCT06665334 | Oct 2024 → Oct 2026 expected | colorectal cancer | Fudan University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT05498766 | Jul 2024 → Jul 2029 expected | gastric cancer | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06368063 | May 2024 → Mar 2026 overdue | pancreas disorder | Xi'an Jiaotong University | Recruiting | No outcome recorded |
| Phase 4 | NCT06387368 | May 2024 → Mar 2028 expected | malignant pancreatic neoplasm | Xi'an Jiaotong University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT05860907 | Oct 2023 → Oct 2025 overdue | breast cancer | Fudan University | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT05839314 | May 2023 → May 2027 expected | idiopathic membranous glomerulonephritis | Chinese PLA General Hospital | Recruiting | No outcome recorded |
| Phase 4 | NCT04790305 | Jun 2021 → Dec 2027 expected | invasive ductal breast carcinoma, triple-negative breast carcinoma | Fudan University | Recruiting | No outcome recorded |
| Phase 4 | NCT02627248 | Oct 2015 → Oct 2025 | breast cancer | Shandong University | Unknown | No outcome recorded |
| Phase 4 | NCT02615457 | Oct 2015 → Oct 2025 | triple-negative breast carcinoma | Shandong University | Unknown | No outcome recorded |
| Phase 4 | NCT01760616 | Nov 2011 → Aug 2015 | carcinoma of liver and intrahepatic biliary tract | Qidong Gaitianli Medicines Co., Ltd | Terminated | No outcome recorded Stop: Enrollment |
| Phase 4 | NCT01770431 | Aug 2011 → Aug 2016 | carcinoma of liver and intrahepatic biliary tract | Qidong Gaitianli Medicines Co., Ltd | Completed | Met primary |
| Phase not applicable3 trials | ||||||
| — | NCT05749211 | May → Dec 2023 | ovarian cancer | Ruijin Hospital | Unknown | No outcome recorded |
| — | NCT05792254 | May → Dec 2023 | fallopian tube cancer, ovarian cancer, peritoneum cancer | Ruijin Hospital | Unknown | No outcome recorded |
| — | NCT03198117 | Apr → Nov 2017 | non-small cell lung carcinoma | Qidong Gaitianli Medicines Co., Ltd | Terminated | No outcome recorded Stop: Enrollment |
| Comparator or background therapy1 trial | ||||||
| Phase 2 | NCT07355361 Comparator | Jan 2026 → Jun 2027 expected | female breast carcinoma, proteinuria | Fudan University | Not yet recruiting | No outcome recorded |
Evidence & citations 6 cited values
Every value below carries the sentence it was read from. 25 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Huaier Granule | “Drug: Huaier granule” NCT06665334 ↗ |
| Known as | Huaier Granules | “Huaier Granules: Oral administration, 10g once, 3 times a day.” NCT06387368 ↗ |
| Known as | Z20000109 | “Huaier Granule Group: Participants will take Huaier Granule (Z20000109) on top of their standard treatment.” NCT07355361 ↗ |
| Action | Inhibit | “It was observed that the Huaier extract significantly inhibited the spheroid formation potential (P<0.05) and decreased the aldehyde dehydrogenase (ALDH)-positive cell...” PMID 23599758 ↗ Jan 2013 |
| Modality | Traditional medicine (herbal / TCM) | “Huaier Granule is a Chinese medicine” NCT01760616 ↗ |
| Route | Oral | “the Huaier Granule Electuary should be orally taken from the 15th day after surgery” NCT01760616 ↗ |