Drugs / MK3207
last change Mar 2011 re-read 3 minutes ago

MK3207

also known as M3207

Small molecule targets CALCRL via inhibition

Developed for
migraine disorder
Investigated by
Merck Sharp & Dohme LLC

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00548353 Aug 2007 → Apr 2008 migraine disorder Merck Sharp & Dohme LLC Completed No outcome recorded
Phase 21 trial · 1 met primary
Phase 2 NCT00712725 Jul 2008 → Jan 2009 migraine disorder Merck Sharp & Dohme LLC Completed Met primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as MK-3207 “BACKGROUND: This study evaluated the CGRP receptor antagonist MK-3207 for acute treatment of migraine.” PMID 21383045 ↗ Mar 2011
2

NCT00712725 ↗

NCT00548353 ↗

Known as M3207 “M3207 (20 mg); patients will be administered a single dose of 100 mg of MK3207 (i.e., 5 x20-mg tablets).” NCT00548353 ↗
Action Inhibit “BACKGROUND: This study evaluated the CGRP receptor antagonist MK-3207 for acute treatment of migraine.” PMID 21383045 ↗ Mar 2011
1

“Calcitonin gene-related peptide type 1 receptor antagonist” CHEMBL1910936 ↗

Modality Small molecule — CHEMBL1910936 ↗
Route Oral “MK3207 Orally administered to patients with water.” NCT00548353 ↗
Target CALCRL “Calcitonin gene-related peptide type 1 receptor antagonist” CHEMBL1910936 ↗