Drugs / BIZALIMOGENE RALAPLASMID

Trials 10 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT01188850 Jul 2010 → Oct 2011 human papilloma virus infection Inovio Pharmaceuticals Completed No outcome recorded
Phase 1 NCT00685412 May 2008 → Jan 2011 human papilloma virus infection Inovio Pharmaceuticals Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02163057 Aug 2014 → Jan 2017 head and neck squamous cell carcinoma Inovio Pharmaceuticals Completed No outcome recorded
Phase 25 trials
Phase 2 NCT03603808 Sep 2018 → Dec 2024 squamous cell intraepithelial neoplasia AIDS Malignancy Consortium Completed No outcome recorded
Phase 2 NCT03499795 May 2018 → Jun 2020 anus neoplasm Inovio Pharmaceuticals Completed No outcome recorded
Phase 2 NCT03180684 Aug 2017 → Jul 2020 human papilloma virus infection, precancerous condition, vulvar intraepithelial neoplasia Inovio Pharmaceuticals Completed No outcome recorded
Phase 2 NCT02501278 May 2016 → May 2019 cervical cancer European Organisation for Research and Treatment of Cancer - EORTC Withdrawn No outcome recorded
Phase 2 NCT01304524 Apr 2011 → May 2014 cervical intraepithelial neoplasia Inovio Pharmaceuticals Completed No outcome recorded
Phase 32 trials
Phase 3 NCT03721978 Feb 2019 → Aug 2022 cervical intraepithelial neoplasia grade 2/3, cervical squamous intraepithelial neoplasia Inovio Pharmaceuticals Completed No outcome recorded
Phase 3 NCT03185013 Jun 2017 → Jul 2020 cervical intraepithelial neoplasia grade 2/3 Inovio Pharmaceuticals Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as BIZALIMOGENE RALAPLASMID ChEMBL registry synonym — accepted as the source's own label CHEMBL4297247
Known as Bizalimogen ralaplasmido ChEMBL registry synonym — accepted as the source's own label CHEMBL4297247
Known as Bizalimogene ralaplasmide ChEMBL registry synonym — accepted as the source's own label CHEMBL4297247
Known as PGX-3002 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297247
Known as VGX 3100 “VGX-3100 is an investigational DNA-based immunotherapy being developed as an alternative to surgery and ablation for cervical High-Grade Squamous Intraepithelial Lesion (HSIL)...” PMID 33175656 Nov 2020
10

“6 mg of VGX-3100 (2 separate DNA plasmids respectively encoding E6 and E7 proteins of HPV 16 and HPV 18)” NCT02163057

“INO-3112 i.e. the combination of VGX-3100 and INO-9012, specifically:” NCT02501278

“Biological: VGX 3100NCT01304524

NCT03603808

NCT01188850

NCT00685412

NCT03185013

NCT03721978

NCT03180684

NCT03499795

Modality Vaccine “VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins” PMID 26386540 Sep 2015
Route Intramuscular “given intramuscularly at 0, 4, and 12 weeks” PMID 26386540 Sep 2015