Drugs / Froniglutide
last change Sep 2025 re-read 2 minutes ago

Froniglutide

also known as PB1023 · Glymera · PF1801

Protein / enzyme biologic

Developed for
type 2 diabetes mellitus · dermatomyositis
Investigated by
PhaseBio Pharmaceuticals Inc. · Immunoforge Co. Ltd.

Trials 4 · a red edge is where a trial was stopped

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT01478399 Dec 2011 → Oct 2012 type 2 diabetes mellitus PhaseBio Pharmaceuticals Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01236404 Nov 2010 → Nov 2011 type 2 diabetes mellitus PhaseBio Pharmaceuticals Inc. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05833711 Sep 2023 → Mar 2025 dermatomyositis Immunoforge Co. Ltd. Unknown No outcome recorded
Phase 2 NCT01658501 Jul 2012 → Jul 2013 type 2 diabetes mellitus PhaseBio Pharmaceuticals Inc. Completed No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01427257 Comparator Feb → Sep 2012 type 2 diabetes mellitus PhaseBio Pharmaceuticals Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Froniglutide ClinicalTrials.gov intervention name — accepted as the source's own label NCT05833711
Known as Glymera “Phase 1 Open-Label Pharmacokinetic, Safety and Tolerability Study of a Single Subcutaneous Dose of Glymera (PB1023) Injection in Subjects With Normal Renal Function and...” NCT01478399
Known as PB1023 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01478399
3

NCT01658501

NCT01236404

NCT01427257

Known as PF1801 “Froniglutide (PF1801) 50 mg will be administered subcutaneously once a week.” NCT05833711
Modality Protein / enzyme biologic CHEMBL5314983
Route Subcutaneous Subcutaneous injection PB1023” NCT01236404