Drugs / AMILOMOTIDE
last change Apr 2020 re-read 2 minutes ago

AMILOMOTIDE

also known as CAD106 · Amilomotida

Protein / enzyme biologic targets APP

Developed for
Alzheimer disease
Investigated by
Novartis · Novartis Pharmaceuticals · Amgen · Banner Alzheimer's Institute · National Institute on Aging (NIA)

Trials 6 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00411580 Jun 2005 → Dec 2008 Alzheimer disease Novartis Pharmaceuticals Completed No outcome recorded
Phase 24 trials
Phase 2 NCT01023685 Dec 2009 → Feb 2012 Alzheimer disease Novartis Completed No outcome recorded
Phase 2 NCT00956410 Sep 2009 → Jun 2011 Alzheimer disease Novartis Completed No outcome recorded
Phase 2 NCT00795418 Oct 2008 → Nov 2010 Alzheimer disease Novartis Completed No outcome recorded
Phase 2 NCT00733863 Jul 2008 → Feb 2010 Alzheimer disease Novartis Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02565511 Nov 2015 → Apr 2020 Alzheimer disease Novartis Pharmaceuticals Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT01097096 Comparator Mar 2010 → Dec 2012 Alzheimer disease Novartis Pharmaceuticals Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as AMILOMOTIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL2108328
Known as Amilomotida ChEMBL registry synonym — accepted as the source's own label CHEMBL2108328
Known as CAD106 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01097096
6

NCT00411580

NCT02565511

NCT00956410

NCT00733863

NCT01023685

NCT00795418

Modality Protein / enzyme biologic CHEMBL2108328
Route Subcutaneous “Each patient received three subcutaneous injections.” PMID 22677258 Jun 2012
Target APP “Amyloid-beta A4 protein vaccine antigen” CHEMBL2108328