Drugs / canfosfamide
canfosfamide
also known as
TLK286 · Telcyta · Canfosfamida · canfosfamide HCl · CANFOSFAMIDE HYDROCHLORIDE · Canfosfamidhydrochloride · TELCYTA(TM) · TER-286 · +1 more
Trials 15
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/25 trials | ||||||
| Phase 1/2 | NCT00088556 | Aug 2004 → May 2009 | non-small cell lung carcinoma | Telik | Completed | No outcome recorded |
| Phase 1/2 | NCT00077883 | Feb 2004 → Mar 2007 | non-small cell lung carcinoma | Telik | Completed | No outcome recorded |
| Phase 1/2 | NCT00052065 | Feb 2003 → Mar 2006 | ovarian neoplasm | Telik | Completed | No outcome recorded |
| Phase 1/2 | NCT00051948 | Jan 2003 → Jan 2005 | ovarian cancer | Telik | Completed | No outcome recorded |
| Phase 1/2 | NCT00047801 | Oct 2002 → Sep 2004 | non-small cell lung carcinoma | Telik | Completed | No outcome recorded |
| Phase 26 trials | ||||||
| Phase 2 | NCT01148108 | Jun 2010 → Sep 2012 | mantle cell lymphoma, plasma cell myeloma | Telik | Completed | No outcome recorded |
| Phase 2 | NCT00040638 | Jul 2002 → Aug 2003 | non-small cell lung carcinoma | Telik | Completed | No outcome recorded |
| Phase 2 | NCT00035841 | Apr 2002 → Jul 2004 | breast cancer | Telik | Completed | No outcome recorded |
| Phase 2 | NCT00036920 | Jan → Aug 2002 | lung cancer | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 2 | NCT00038428 | Jun 2001 → Jul 2005 | ovarian neoplasm | Telik | Completed | No outcome recorded |
| Phase 2 | NCT00022347 | May 2001 → Apr 2004 | fallopian tube cancer, ovarian cancer, peritoneum cancer | Memorial Sloan Kettering Cancer Center | Completed | No outcome recorded |
| Phase 34 trials · 1 missed | ||||||
| Phase 3 | NCT00350948 | May 2006 → Dec 2008 | ovarian neoplasm | Telik | Terminated | Missed primary Stop: Business |
| Phase 3 | NCT00102973 | Dec 2004 → Jul 2008 | ovarian neoplasm | Telik | Completed | No outcome recorded |
| Phase 3 | NCT00057720 | Jun 2003 → Dec 2006 | ovarian neoplasm | Telik | Completed | No outcome recorded |
| Phase 3 | NCT00080340 | ? → May 2005 | non-small cell lung carcinoma | Telik | Completed | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 17 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | canfosfamide | “Canfosfamide is a novel glutathione analog activated by glutathione S-transferase P1-1.” PMID 20222977 ↗ Mar 2010 |
| Known as | Canfosfamida | ChEMBL registry synonym — accepted as the source's own label CHEMBL2111086 ↗ |
| Known as | canfosfamide HCl | “30 min. intravenous infusion of canfosfamide HCl (1000 mg/m2) every 2 weeks” NCT01148108 ↗ |
| Known as | CANFOSFAMIDE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL2111086 ↗ |
| Known as | Canfosfamidhydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL2111086 ↗ |
| Known as | Telcyta | “TLK286 (Telcyta) in Combination With Carboplatin (Paraplatin) Versus Doxil in Platinum Refractory or Resistant Ovarian Cancer” NCT00102973 ↗3“TLK286 (Telcyta) vs. Doxil/Caelyx or Hycamtin in Platinum Refractory or Resistant Ovarian Cancer” NCT00057720 ↗ “TLK286 (Telcyta) HCl for Injection” NCT00080340 ↗ |
| Known as | TELCYTA(TM) | “The purpose of this study was to determine the safety and efficacy of TLK286 (TELCYTA(TM)), a glutathione analog prodrug, in patients with platinum and paclitaxel refractory or...” PMID 16014111 ↗ Jul 2005 |
| Known as | TER-286 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2111086 ↗ |
| Known as | TLK286 | “The purpose of this study was to determine the safety and efficacy of TLK286 (TELCYTA(TM)), a glutathione analog prodrug, in patients with platinum and paclitaxel refractory or...” PMID 16014111 ↗ Jul 2005 |
| Known as | TLK286 HCl | “TLK286 HCl for injection” NCT00057720 ↗ |
| Modality | Small molecule | “a glutathione analog prodrug” PMID 16014111 ↗ Jul 2005 |
| Route | Intravenous | “TLK286 IV over 30 minutes” NCT00022347 ↗ |