Drugs / PXL770
last change Sep 2024 re-read 3 minutes ago

PXL770

Developed for
NAFLD1 · adrenomyeloneuropathy · metabolic disease
Investigated by
Poxel SA

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT05441904 Mar 2021 metabolic dysfunction-associated steatohepatitis Poxel SA Completed No outcome recorded
Phase 1 NCT03950882 Aug 2019 → Mar 2020 NAFLD1 Poxel SA Completed No outcome recorded
Phase 1 NCT03886103 Feb → Mar 2019 — Poxel SA Completed No outcome recorded
Phase 1 NCT03395470 Aug 2017 → Mar 2018 metabolic disease Poxel SA Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05146284 Sep 2023 → Sep 2024 adrenomyeloneuropathy Poxel SA Withdrawn No outcome recorded Stop: Business
Phase 2 NCT03763877 Mar 2019 → Aug 2020 NAFLD1 Poxel SA Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as PXL770 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03950882 ↗
5

NCT05146284 ↗

NCT03763877 ↗

NCT03886103 ↗

NCT05441904 ↗

NCT03395470 ↗

Action Activate “PXL770 is a direct activator of 5' adenosine monophosphate-activated protein kinase (AMPK)” NCT03395470 ↗
Route Oral “to receive oral PXL770 250 mg once daily, 250 mg twice daily, or 500 mg once daily, or matched placebo” PMID 34560015 ↗ Sep 2021