Drugs / IONIS DGAT2Rx
last change Jun 2020 re-read 3 minutes ago

IONIS DGAT2Rx

Antisense oligonucleotide targets DGAT2 via inhibition

Developed for
fatty liver disease
Investigated by
Ionis Pharmaceuticals, Inc.

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT03334214 Nov 2017 → Nov 2018 fatty liver disease Ionis Pharmaceuticals, Inc. Completed Met primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as IONIS-DGAT2Rx “IONIS-DGAT2Rx is an antisense oligonucleotide inhibitor of DGAT2 that is under clinical investigation for the treatment of non-alcoholic fatty liver disease (NAFLD) and...” PMID 32553151 ↗ Jun 2020
1

NCT03334214 ↗

Action Inhibit “antisense oligonucleotide inhibitor of DGAT2” PMID 32553151 ↗ Jun 2020
Modality Antisense oligonucleotide “IONIS-DGAT2Rx is an antisense oligonucleotide inhibitor of DGAT2” PMID 32553151 ↗ Jun 2020
Route Subcutaneous “once weekly subcutaneous injection of 250 mg IONIS-DGAT2Rx” PMID 32553151 ↗ Jun 2020
Target DGAT2 “antisense oligonucleotide inhibitor of DGAT2” PMID 32553151 ↗ Jun 2020