Drugs / SIMENEPAG ISOPROPYL
last change Oct 2011 re-read 2 minutes ago

SIMENEPAG ISOPROPYL

also known as AGN-210669

Small molecule targets PTGER2 via activation

Developed for
ocular hypertension · open-angle glaucoma · glaucoma
Investigated by
Allergan

Trials 3 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00809848 Feb → May 2009 glaucoma, ocular hypertension Allergan Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01291108 Apr → Oct 2011 ocular hypertension, open-angle glaucoma Allergan Completed No outcome recorded
Phase 2 NCT01001195 Nov 2009 → Apr 2010 ocular hypertension, open-angle glaucoma Allergan Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as SIMENEPAG ISOPROPYL ChEMBL registry synonym — accepted as the source's own label CHEMBL2105710
Known as AGN-210669 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00809848
2

NCT01291108

NCT01001195

Action Activate “Prostanoid EP2 receptor agonist” CHEMBL2105710
Modality Small molecule CHEMBL2105710
Route Topical “applied as 1 drop in both eyes every evening during Month 1 or Month 2” NCT01291108
Target PTGER2 “Prostanoid EP2 receptor agonist” CHEMBL2105710