Drugs / MART-1 antigen

Trials 23 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT02320305 Jan → Dec 2015 cutaneous melanoma Mayo Clinic Completed No outcome recorded
Phase 0 NCT01748747 Oct 2012 → Dec 2014 melanoma Mayo Clinic Completed No outcome recorded
Phase 15 trials
Phase 1 NCT01176461 Aug 2010 → Dec 2016 cutaneous melanoma H. Lee Moffitt Cancer Center and Research Institute Completed No outcome recorded
Phase 1 NCT00470015 Mar 2007 → Apr 2009 cutaneous melanoma Mayo Clinic Completed No outcome recorded
Phase 1 NCT00037037 Oct 2001 → ? cutaneous melanoma Herbert Irving Comprehensive Cancer Center Unknown No outcome recorded
Phase 1 NCT00005841 Jun → Dec 2000 cutaneous melanoma, ocular melanoma University of Southern California Terminated No outcome recorded
Phase 1 NCT00003792 Apr 1999 → Oct 2006 cutaneous melanoma Baylor Health Care System Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT01082198 Oct 2002 → Apr 2010 cutaneous melanoma Maria Sklodowska-Curie National Research Institute of Oncology Unknown No outcome recorded
Phase 1/2 NCT00019214 Apr 1997 → Jul 2006 cutaneous melanoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 1/2 NCT00002952 Jan 1997 → Aug 2002 cutaneous melanoma University of Chicago Completed No outcome recorded
Phase 212 trials
Phase 2 NCT01307618 Feb 2011 → Jan 2015 melanoma National Cancer Institute (NCI) Terminated No outcome recorded
Phase 2 NCT00295958 Dec 2005 → Jun 2006 cutaneous melanoma National Institutes of Health Clinical Center (CC) Completed No outcome recorded
Phase 2 NCT00303836 Nov 2005 → Jan 2007 metastatic melanoma National Cancer Institute (NCI) Terminated No outcome recorded
Phase 2 NCT00089063 Jun 2004 → Jun 2007 iris melanoma, medium/large size posterior uveal melanoma, ocular melanoma with extraocular extension National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00334776 Oct 2003 → Jun 2005 cutaneous melanoma, ocular melanoma University of Southern California Completed No outcome recorded
Phase 2 NCT00031733 Feb 2002 → Dec 2004 cutaneous melanoma, ocular melanoma University of Southern California Completed No outcome recorded
Phase 2 NCT00020475 Feb 2001 → Mar 2007 ocular melanoma with extraocular extension National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00006385 Sep 2000 → Oct 2006 cutaneous melanoma Eastern Cooperative Oncology Group Completed No outcome recorded
Phase 2 NCT00019994 Oct 1999 → Oct 2007 cutaneous melanoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 2 NCT00006113 Jun 1999 → May 2003 cutaneous melanoma University of Southern California Terminated No outcome recorded
Phase 31 trial
Phase 3 NCT00036816 Feb 2002 → Feb 2003 uveal melanoma European Organisation for Research and Treatment of Cancer - EORTC Terminated No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00091338 Background Aug 2004 → ? cutaneous melanoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 1 NCT00025181 Background Oct 2001 → Jan 2003 cutaneous melanoma, ocular melanoma University of Southern California Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 27 sources stand behind the page.

FieldValueCited text
Known as MART-1 antigen ClinicalTrials.gov intervention name — accepted as the source's own label NCT00303836
13

NCT01748747

NCT00031733

NCT00470015

NCT00025181

NCT00089063

NCT00002952

NCT00091338

NCT00020475

NCT00019721

NCT00005841

NCT00019994

NCT02320305

NCT00037037

Known as HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT01082198
Known as MART-1 “The melanoma tumor antigen epitope peptides MART-1(26-35 (27L)), gp100(209-217 (210M)),and tyrosinase(368-376 (370D)) were emulsified with incomplete Freund's adjuvant and...” PMID 12684398 Apr 2003
10

NCT01307618

NCT00019214

NCT00003792

NCT01176461

NCT00295958

NCT00006385

NCT00019396

NCT00006113

NCT00036816

NCT00334776

Known as MART-1a “melanoma-associated peptide (MART-1a)” PMID 32752904 Aug 2020
Action Deplete “Vaccines made from peptides may make the body build an immune response to kill tumor cells.” NCT00089063
Modality Vaccine “melanoma peptide vaccine comprising tyrosinase:368-376 peptide, gp100:209-217 antigen, and MART-1:26-35 antigen emulsified in Montanide ISA-51” NCT00005841
Route Subcutaneous “Patients receive melanoma peptide vaccine comprising tyrosinase:368-376 peptide, gp100:209-217 antigen, and MART-1:26-35 antigen emulsified in Montanide ISA-51 subcutaneously...” NCT00005841