Drugs / Lenrispodun
Lenrispodun
also known as
ITI-214 · IC 200214-12 · IC-200214 · IC200214 phosphate · ITI- 12-phosphate · ITI-002 · ITI-12-Cyclo-(S,R) phosphate · ITI-214 FREE BASE · +5 more
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT03489772 | Jul 2018 → Aug 2019 | — | Intra-Cellular Therapies, Inc. | Completed | No outcome recorded |
| Phase 1 | NCT01900522 | Jul 2013 → Sep 2014 | schizophrenia | Takeda | Terminated | No outcome recorded Stop: Business |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT03387215 | Jul 2018 → Mar 2020 | systolic heart failure | Intra-Cellular Therapies, Inc. | Completed | No outcome recorded |
| Phase 1/2 | NCT03257046 | Sep 2017 → Sep 2018 | Parkinson disease | Intra-Cellular Therapies, Inc. | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT05766813 | Mar 2023 → Oct 2025 | Parkinson disease | Intra-Cellular Therapies, Inc. | Completed | No outcome recorded |
Evidence & citations 17 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Lenrispodun | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05766813 ↗ |
| Known as | IC 200214-12 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | IC-200214 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | IC200214 phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI- 12-phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI-002 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI-12-Cyclo-(S,R) phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI-214 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01900522 ↗ |
| Known as | ITI-214 FREE BASE | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI-214 phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI-214F | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | ITI200214-phosphate | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | LENRISPODUN PHOSPHATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Known as | PDE1-IN-1 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3769414 ↗ |
| Action | Inhibit | “ITI-214 is a highly selective PDE1 inhibitor” PMID 34461742 ↗ Aug 2021 |
| Modality | Small molecule | — CHEMBL3769414 ↗ |
| Route | Oral | “administered as multiple doses of oral solution” NCT01900522 ↗ |