Drugs / Autologous CD19/CD22 CAR T cells
last change Aug 2025 re-read 3 minutes ago

Autologous CD19/CD22 CAR T cells

Cell therapy

Developed for
precursor lymphoblastic lymphoma/leukemia
Investigated by
Instituto de Investigación Hospital Universitario La Paz

Trials 1

20262027202820292030
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06709469 Jul 2025 → Jun 2030 expected precursor lymphoblastic lymphoma/leukemia Instituto de Investigación Hospital Universitario La Paz Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Autologous CD19/CD22 CAR T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT06709469 ↗
Known as CART-19/22 “In the present study (ReALL\_CART), we propose an umbrella design methodology using autologous dual CART-19/22 for CD19+/-CD22+/- relapse after CART19 or allogeneic CART-NKG2D...” NCT06709469 ↗
Known as dual CART-19/22 “In the present study (ReALL\_CART), we propose an umbrella design methodology using autologous dual CART-19/22 for CD19+/-CD22+/- relapse after CART19 or allogeneic CART-NKG2D...” NCT06709469 ↗
Known as tandem anti-CD19/CD22 CAR T-cells “METHODS: We report Spanish clinical data on the safety and efficacy of tandem anti-CD19/CD22 CAR T-cells administered on a compassionate use basis in a cohort of 10 heavily...” PMID 40753722 ↗ Aug 2025
Modality Cell therapy “autologous CD19/CD22 CAR T cells” NCT06709469 ↗
Route Intravenous “unfrozen cells (same dose) if there has been no ≥ grade 1 cytokine-release syndrome (CRS) in the next 72 h; intravenously.” NCT06709469 ↗