Drugs / TAS-115
last change May 2026 re-read 2 minutes ago

TAS-115

also known as Pamufetinib

Small molecule targets KDR, MET via inhibition

Trials 0

Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04999761 Background Jun 2021 → May 2026 overdue alveolar soft part sarcoma, biliary tract cancer, colorectal cancer, esophageal cancer +4 Taiho Pharmaceutical Co., Ltd. Recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as TAS-115 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04999761
Known as Pamufetinib ChEMBL registry synonym — accepted as the source's own label CHEMBL3764045
Action Inhibit “Vascular endothelial growth factor receptor 2 inhibitor” CHEMBL3764045
1

“Hepatocyte growth factor receptor inhibitor” CHEMBL3764045

Modality Small molecule CHEMBL3764045
Route Oral “administered orally” NCT04999761
Target KDR “Vascular endothelial growth factor receptor 2 inhibitor” CHEMBL3764045
Target MET “Hepatocyte growth factor receptor inhibitor” CHEMBL3764045