Drugs / OPL-CCL2-LPM
last change Jun 2010 re-read 3 minutes ago

OPL-CCL2-LPM

Protein / enzyme biologic

Developed for
IgA glomerulonephritis · proteinuria
Investigated by
Osprey Pharmaceuticals USA, Inc.

Trials 1

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00856674 Mar 2009 → Jun 2010 IgA glomerulonephritis, proteinuria Osprey Pharmaceuticals USA, Inc. Terminated No outcome recorded Stop: Enrollment

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as OPL-CCL2-LPM ClinicalTrials.gov intervention name — accepted as the source's own label NCT00856674 ↗
Action Inhibit “an enzyme that inhibits protein production by the leukocytes and prevents the leukocytes from migrating into the kidney” NCT00856674 ↗
Modality Protein / enzyme biologic “CCL2-LPM is composed of the messenger chemokine, CCL2, fused to an enzyme” NCT00856674 ↗
Route Intravenous “intravenous 0.001 mg/kg, 0.01 mg/kg, 0.05 mg/kg, 0.1 mg/kg, 0.5 mg/kg, 1 mg/kg” NCT00856674 ↗