Drugs / NTR-441
last change Oct 2025 re-read 3 minutes ago

NTR-441

Developed for
COVID-19
Investigated by
Neutrolis

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04941183 Apr 2021 → Dec 2022 COVID-19 Neutrolis Terminated No outcome recorded Stop: Enrollment

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-10-29 Neutrolis Results Neutrolis Presented First-in-Human Proof-of-Concept Data Validating DNASE1L3-Mediated Neutrophil Extracellular Trap (NET) Clearance as a Therapeutic Approach in Autoimmunity at American College of Rheumatology Convergence 2025 neutrolis.com ↗
today announced positive first-in-human clinical data demonstrating that its DNASE1L3 analogue achieved rapid, multi-organ clinical improvement and robust target engagement consistent with its mechanism of NET degradation.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as NTR-441 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04941183 ↗
Route Intravenous “after single ascending IV infusion doses” NCT04941183 ↗