Drugs / TransCon TLR7/8 Agonist
last change Mar 2025 re-read 3 minutes ago

TransCon TLR7/8 Agonist

also known as TC TLR7/8

targets TLR7 via activation

Developed for
head and neck squamous cell carcinoma
Investigated by
Ascendis Pharma A/S

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05980598 Sep 2023 → Mar 2025 head and neck squamous cell carcinoma Ascendis Pharma A/S Terminated No outcome recorded Stop: Enrollment

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TransCon TLR7/8 Agonist ClinicalTrials.gov intervention name — accepted as the source's own label NCT05980598 ↗
Known as TC TLR7/8 “TransCon (TC) TLR7/8 Agonist, TC IL-2 β/γ, Pembrolizumab Prior to Surgery for Advanced Head and Neck Squamous Cell Carcinoma” NCT05980598 ↗
Action Activate “TLR7/8 agonist prodrug” NCT05980598 ↗
Route Other “TransCon TLR7/8 Agonist intratumoral (IT) injection” NCT05980598 ↗
Target TLR7 “TLR7/8 agonist prodrug” NCT05980598 ↗