Drugs / Gene Modified T Cells
last change Dec 2018 re-read 2 minutes ago

Gene Modified T Cells

Cell therapy

Developed for
breast cancer · colorectal cancer · gastric cancer · metastatic malignant neoplasm · prostate cancer
Investigated by
Roger Williams Medical Center

Trials 5 · a red edge is where a trial was stopped

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT00673322 May 2008 → Aug 2012 colorectal cancer Roger Williams Medical Center Terminated No outcome recorded
Phase 1 NCT00673829 May 2008 → Dec 2017 breast cancer Roger Williams Medical Center Suspended No outcome recorded
Phase 1 NCT00664196 Apr 2008 → Dec 2017 prostate cancer Roger Williams Medical Center Suspended No outcome recorded
Phase 1 NCT00429078 Jul 2007 → Apr 2011 gastric cancer Roger Williams Medical Center Withdrawn No outcome recorded
Phase 21 trial
Phase 2 NCT01723306 Oct 2012 → Oct 2016 metastatic malignant neoplasm Roger Williams Medical Center Suspended No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Gene Modified T Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT00664196
3

NCT01723306

NCT00673322

NCT00673829

Known as 2nd Generation Designer T Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT00429078
Action Deplete “These modified cells are then re infused back into the participant so that they can attack and kill tumor cells.” NCT00429078
Modality Cell therapy “Designer T cells are prepared by removing white blood cells from the participant, and then modifying these cells” NCT00429078
Route Intravenous “given through a vein in the arm or a catheter” NCT00664196