Drugs / CLATURAFENIB
last change Jun 2026 re-read 9 days ago

CLATURAFENIB

also known as PF-07799933 · ARRY-440

Small molecule

Developed for
melanoma · non-small cell lung carcinoma · brain neoplasm · colorectal cancer · differentiated thyroid carcinoma · glioma · low grade glioma · malignant glioma
+1 more · thyroid cancer
Investigated by
Pfizer

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07563894 Apr → Jun 2026 — Pfizer Completed No outcome recorded
Phase 1 NCT05538130 Nov 2022 → Aug 2027 expected brain neoplasm, differentiated thyroid carcinoma, low grade glioma, malignant glioma +2 Pfizer Active not recruiting No outcome recorded
Phase 1 NCT05355701 Jul 2022 → Aug 2027 expected colorectal cancer, glioma, melanoma, non-small cell lung carcinoma +1 Pfizer Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as CLATURAFENIB ChEMBL registry synonym — accepted as the source's own label CHEMBL6068425 ↗
Known as ARRY-440 ChEMBL registry synonym — accepted as the source's own label CHEMBL6068425 ↗
Known as PF-07799933 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07563894 ↗
2

NCT05538130 ↗

NCT05355701 ↗

Modality Small molecule — CHEMBL6068425 ↗
Route Oral “PF-07799933 comes as a tablet to take by mouth, 2 times a day.” NCT05355701 ↗