Drugs / IDE161
last change Oct 2025 re-read 2 minutes ago

IDE161

targets PARG via inhibition

Developed for
small cell lung carcinoma · breast cancer · colorectal cancer · endometrial cancer · head and neck cancer · non-small cell lung carcinoma · ovarian cancer · prostate cancer
Investigated by
IDEAYA Biosciences · Merck Sharp & Dohme LLC

Trials 2 · a red edge is where a trial was stopped

202420252026202720282029
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05787587 Apr 2023 → Oct 2026 expected breast cancer, colorectal cancer, endometrial cancer, head and neck cancer +4 IDEAYA Biosciences Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT07174583 Oct 2025 → Jul 2029 expected small cell lung carcinoma IDEAYA Biosciences Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as IDE161 “PARG Inhibitor IDE161NCT05787587
2

NCT07174583

NCT05787587

Action Inhibit “PARG Inhibitor IDE161” NCT05787587
Route Oral oral administration” NCT07174583
Target PARG PARG Inhibitor IDE161” NCT05787587