Drugs / cross-linked hyaluronic acid
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT07520539 | Jul → Dec 2026 expected | gingival recession | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT05429229 | Nov 2021 → Dec 2023 | diabetic retinopathy, disorder of defective peroxisome oxidative status, dry eye syndrome | Adolfo Daniel Rodriguez-Carrizalez | Unknown | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT06517667 | Nov 2023 → Feb 2024 | dry eye syndrome | University of Seville | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT05727371 | Aug 2023 → Feb 2026 overdue | osteoarthritis, knee | RegenLab France SAS | Active not recruiting | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT07715331 Comparator | Jan 2025 → Feb 2026 | gingival disorder | Al-Azhar University | Completed | No outcome recorded |
Evidence & citations 3 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Cross-Linked Hyaluronic Acid | “It consists of a preservative-free eye drop composed of 100 mg cross-linked hyaluronic acid, 100 mg coenzyme Q10, 500 mg vitamin E TPGS (D-alpha-tocopheryl polyethylene glycol...” NCT05429229 ↗4“combination of cross-linked hyaluronic acid (HA) with autologous platelet-rich plasma (PRP) obtained with the RegenMatrix medical device” NCT05727371 ↗ “Tear substitute based on 0.20% Cross-linked hyaluronic acid” NCT06517667 ↗ |
| Known as | Juvéderm Voluma with Lidocaine | “cross-linked hyaluronic acid filler (Juvéderm Voluma® with Lidocaine)” NCT07715331 ↗ |
| Route | Topical | “preservative-free eye drop composed of 100 mg cross-linked hyaluronic acid” NCT05429229 ↗ |