Drugs / M28z1XXPD1DNR
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M28z1XXPD1DNR

Developed for
malignant pleural mesothelioma
Investigated by
Atara Biotherapeutics · Memorial Sloan Kettering Cancer Center

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04577326 Sep 2020 → Sep 2026 overdue malignant pleural mesothelioma Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2021-12-09 Atara Biotherapeutics Results Atara Biotherapeutics Announces Preliminary Results for ATA2271, a Next-Generation Autologous Mesothelin-targeted CAR T-cell Therapy for Solid Tumors, at ESMO Immuno-Oncology Congress 2021 atarabio.com ↗
Importantly, ATA2271 CAR T-cells persisted in patients’ peripheral blood for greater than four weeks and was associated with upregulated effector cytokines.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as M28z1XXPD1DNR “A single dose of M28z1XXPD1DNR CAR T cells will be instilled into the pleural cavity via a pleural catheter or through an interventional radiology-guided needle.” NCT04577326 ↗
Route Other “M28z1XXPD1DNR CAR T cells will be instilled into the pleural cavity” NCT04577326 ↗