Drugs / BMS-986263
last change Feb 2024 re-read 2 minutes ago

BMS-986263

Small interfering RNA (siRNA)

Developed for
fibrotic liver disease · metabolic dysfunction-associated steatohepatitis
Investigated by
Bristol-Myers Squibb

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04225936 Jan 2020 → Jun 2021 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT03142165 May → Nov 2017 Bristol-Myers Squibb Completed No outcome recorded
Phase 22 trials
Phase 2 NCT04267393 Mar 2021 → Aug 2023 metabolic dysfunction-associated steatohepatitis Bristol-Myers Squibb Terminated No outcome recorded
Phase 2 NCT03420768 Feb → Dec 2018 cirrhosis of liver, fibrotic liver disease Bristol-Myers Squibb Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as BMS-986263 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03142165
3

NCT04225936

NCT04267393

NCT03420768

Action Inhibit “designed to degrade HSP47 mRNA” PMID 34605045 Dec 2021
Modality Small interfering RNA (siRNA) “a lipid nanoparticle delivering small interfering RNA designed to degrade HSP47 mRNA” PMID 34605045 Dec 2021
Route Intravenous “infused intravenous administration” NCT03142165