Drugs / BMS-986263
last change Feb 2024 re-read 9 days ago

BMS-986263

Small interfering RNA (siRNA)

Developed for
fibrotic liver disease · metabolic dysfunction-associated steatohepatitis
Investigated by
Bristol-Myers Squibb

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04225936 Jan 2020 → Jun 2021 — Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT03142165 May → Nov 2017 — Bristol-Myers Squibb Completed No outcome recorded
Phase 22 trials · 1 missed
Phase 2 NCT04267393 Mar 2021 → Aug 2023 metabolic dysfunction-associated steatohepatitis Bristol-Myers Squibb Terminated No outcome recorded
Phase 2 NCT03420768 Feb → Dec 2018 cirrhosis of liver, fibrotic liver disease Bristol-Myers Squibb Completed Missed primary

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as BMS-986263 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04225936 ↗
3

NCT04267393 ↗

NCT03142165 ↗

NCT03420768 ↗

Action Inhibit “designed to degrade HSP47 mRNA” PMID 34605045 ↗ Dec 2021
Modality Small interfering RNA (siRNA) “a lipid nanoparticle delivering small interfering RNA designed to degrade HSP47 mRNA” PMID 34605045 ↗ Dec 2021
Route Intravenous “infused intravenous administration” NCT03142165 ↗