Drugs / PACANALOTAMAB
last change Apr 2022 re-read 3 minutes ago

PACANALOTAMAB

also known as AMG 420 · BI 836909

Monoclonal antibody

Developed for
plasma cell myeloma · refractory plasma cell neoplasm
Investigated by
Amgen · Boehringer Ingelheim

Trials 2

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03836053 Mar 2019 → Apr 2022 refractory plasma cell neoplasm Amgen Terminated No outcome recorded Stop: Business
Phase 1 NCT02514239 Jul 2015 → Jul 2018 plasma cell myeloma Boehringer Ingelheim Completed No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2019-09-12 Amgen Results Amgen Highlights New Data From KYPROLIS® (carfilzomib) And Oncology Pipeline At IMW 2019 amgen.com ↗
2019-06-02 Amgen Results Amgen Highlights The Versatility Of The BiTE® Immuno-Oncology Platform In Multiple Tumor Types At ASCO 2019 amgen.com ↗
2018-12-04 Amgen Results Amgen Announces First-In-Human Data Evaluating Investigational Novel BiTE® Immunotherapies AMG 420 And AMG 330 At ASH 2018 amgen.com ↗
Amgen (NASDAQ:AMGN) today announced the first clinical results from studies evaluating investigational novel bispecific T cell engager (BiTE ® ) immunotherapies AMG 420 and AMG 330.

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as PACANALOTAMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4650254 ↗
Known as AMG 420 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03836053 ↗
Known as BI 836909 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02514239 ↗
Modality Monoclonal antibody — CHEMBL4650254 ↗
Route Intravenous “administered by continuous i.v. infusion” NCT02514239 ↗