Drugs / IMIGLITAZAR
Trials 6
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT00762957 | Nov → Dec 2004 | diabetes mellitus | Takeda | Terminated | No outcome recorded |
| Phase 3 | NCT00762684 | Nov → Dec 2004 | type 2 diabetes mellitus | Takeda | Terminated | No outcome recorded |
| Phase 3 | NCT00762190 | Nov 2003 → Dec 2004 | type 2 diabetes mellitus | Takeda | Terminated | No outcome recorded |
| Phase 3 | NCT00759720 | Nov 2003 → Dec 2004 | diabetes mellitus | Takeda | Terminated | No outcome recorded |
| Phase 3 | NCT00762112 | Nov 2003 → Dec 2004 | diabetes mellitus | Takeda | Terminated | No outcome recorded |
| Phase 3 | NCT00763022 | Nov 2003 → Dec 2004 | type 2 diabetes mellitus | Takeda | Completed | No outcome recorded |
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 7 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | IMIGLITAZAR | ChEMBL registry synonym — accepted as the source's own label CHEMBL592054 ↗ |
| Known as | TAK-559 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00762190 ↗ |
| Action | Activate | “TAK-559 has partial peroxisome proliferator-activated receptor-alpha agonist activity, potent peroxisome proliferator-activated receptor-alpha activity, and modest peroxisome...” NCT00759720 ↗2“Peroxisome proliferator-activated receptor alpha agonist” CHEMBL592054 ↗ “Peroxisome proliferator-activated receptor gamma agonist” CHEMBL592054 ↗ |
| Modality | Small molecule | “TAK-559 is a novel oxyiminoalkanoic acid under investigation for use as an oral agent in the treatment of patients with type 2 diabetes mellitus.” NCT00759720 ↗ |
| Route | Oral | “TAK-559 16 mg, tablets, orally, once daily and glyburide stable dose orally, once daily for up to 26 weeks.” NCT00759720 ↗ |
| Target | PPARA | “Peroxisome proliferator-activated receptor alpha agonist” CHEMBL592054 ↗ |
| Target | PPARG | “Peroxisome proliferator-activated receptor gamma agonist” CHEMBL592054 ↗ |