Drugs / MGTA-117
last change Feb 2023 re-read 3 minutes ago

MGTA-117

Developed for
acute myeloid leukemia · myelodysplastic syndrome
Investigated by
Magenta Therapeutics, Inc.

Trials 1

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05223699 Feb 2022 → Feb 2023 acute myeloid leukemia, myelodysplastic syndrome Magenta Therapeutics, Inc. Terminated No outcome recorded Stop: Business

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2022-12-14 Heidelberg Pharma AG Results PR: Encouraging Clinical Data from Two Antibody Drug Conjugates Based on Heidelberg Pharma’s ATAC Technology Presented at the ASH Annual Meeting 2022 heidelberg-pharma.com ↗
Preliminary results from 15 patients across three dose-escalation cohorts showed target cell depletion in the blood and bone marrow, providing evidence of an active dose.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as MGTA-117 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05223699 ↗
Action Deplete “selectively deplete CD117-positive cells” NCT05223699 ↗
Route Intravenous “MGTA-117 will be administered as an IV infusion” NCT05223699 ↗