Drugs / Ozagrel
last change Oct 2017 re-read 9 days ago

Ozagrel

also known as KCT-0809

Small molecule targets TBXAS1 via inhibition

Developed for
dry eye syndrome · cerebral infarction
Investigated by
Kissei Pharmaceutical Co., Ltd.

Trials 7

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 24 trials
Phase 2 NCT01692145 — dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01890941 ? → Mar 2014 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01211951 — dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01427816 — dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 33 trials
Phase 3 NCT02503189 ? → Jan 2017 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 3 NCT02503176 ? → May 2017 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Terminated No outcome recorded
Phase 3 NCT02503163 ? → Oct 2017 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 4 NCT00200356 Comparator Aug 2004 → Oct 2006 cerebral infarction Tanabe Pharma Corporation Completed Met primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Ozagrel ClinicalTrials.gov intervention name — accepted as the source's own label NCT00200356 ↗
Known as KCT-0809 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02503176 ↗
6

NCT02503189 ↗

NCT01890941 ↗

NCT01692145 ↗

NCT01211951 ↗

NCT02503163 ↗

NCT01427816 ↗

Action Inhibit “sodium ozagrel (ozagrel), a thromboxane A(2) synthase inhibitor” PMID 19321945 ↗ Mar 2009
1

“Thromboxane-A synthase inhibitor” CHEMBL11662 ↗

Modality Small molecule — CHEMBL11662 ↗
Route Intravenous “is intravenously administered” NCT00200356 ↗
Target TBXAS1 “Thromboxane-A synthase inhibitor” CHEMBL11662 ↗