Drugs / Ozagrel
last change Oct 2017 re-read 2 minutes ago

Ozagrel

also known as KCT-0809

Small molecule targets TBXAS1 via inhibition

Developed for
dry eye syndrome · cerebral infarction
Investigated by
Kissei Pharmaceutical Co., Ltd.

Trials 7 · a red edge is where a trial was stopped

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 24 trials
Phase 2 NCT01692145 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01427816 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01890941 ? → Mar 2014 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 2 NCT01211951 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 33 trials
Phase 3 NCT02503189 ? → Jan 2017 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 3 NCT02503163 ? → Oct 2017 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Completed No outcome recorded
Phase 3 NCT02503176 ? → May 2017 dry eye syndrome Kissei Pharmaceutical Co., Ltd. Terminated No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 4 NCT00200356 Comparator Aug 2004 → Oct 2006 cerebral infarction Tanabe Pharma Corporation Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Ozagrel ClinicalTrials.gov intervention name — accepted as the source's own label NCT00200356
Known as KCT-0809 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01890941
6

NCT02503176

NCT02503163

NCT01211951

NCT02503189

NCT01692145

NCT01427816

Action Inhibit “sodium ozagrel (ozagrel), a thromboxane A(2) synthase inhibitor” PMID 19321945 Mar 2009
1

“Thromboxane-A synthase inhibitor” CHEMBL11662

Modality Small molecule CHEMBL11662
Route Intravenous “is intravenously administered” NCT00200356
Target TBXAS1 “Thromboxane-A synthase inhibitor” CHEMBL11662