Drugs / Procaine
last change Aug 2026 re-read 2 minutes ago

Procaine

also known as SP01A · Anestil · Enpro · Gero · Jenacaine · Medaject · Naucaine · Neocaine · +15 more

Small molecule

Developed for
HIV infectious disease · osteoarthritis · stomatitis
Investigated by
Samaritan Pharmaceuticals, Inc · Sf Luca Chronic Disease Hospital · Yonsei University

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN 1952-09-19 fda.gov

Trials 5 · a red edge is where a trial was stopped

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00299338 Sep 1997 → Sep 2001 HIV infectious disease Samaritan Pharmaceuticals, Inc Completed No outcome recorded
Phase 22 trials
Phase 2 NCT00299897 Mar 2006 → ? HIV infectious disease Samaritan Pharmaceuticals, Inc Unknown No outcome recorded
Phase 2 NCT00113412 May 2005 → ? HIV infectious disease Samaritan Pharmaceuticals, Inc Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT06717724 Feb → Jun 2024 osteoarthritis Sf Luca Chronic Disease Hospital Completed No outcome recorded
Phase not applicable1 trial
NCT01845532 Apr → Nov 2013 leiomyoma Yonsei University Completed No outcome recorded
Also used as a comparator or background therapy in 5 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT02735317 Comparator Apr 2016 → Jun 2017 nasopharyngeal neoplasm, stomatitis Yun-fei Xia Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03838068 Background Jan 2017 → Dec 2018 exposure, dental pulp Gihan M Abuelniel ,PhD Completed No outcome recorded
Phase 41 trial
Phase 4 NCT06425978 Background May 2024 → May 2026 overdue Fundacion Dexeus Recruiting No outcome recorded
Phase not applicable2 trials
NCT06617065 Background Sep 2024 → Jan 2025 overdue chronic pain syndrome The Seekers Centre Active not recruiting No outcome recorded
NCT02726620 Background Jan → Dec 2017 hypotensive disorder Vanderbilt University Medical Center Completed No outcome recorded

Evidence & citations 26 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as Procaine “Solutions contain either 0.3% Ropivacaine, 1% Procaine, 0.5% Lidocaine, 0.25% Bupivacaine, or a mixture of 0.25% Bupivacaine and 2% Lidocaine in a 9:1 ratio.” NCT06617065
7

“Trigger point injection with 25G needle on the shoulder before surgery(0.5% procaine, 0.25\~0.5% lidocaine, 0.125% bupivacaine)” NCT01845532

“A Pharmacokinetic and Safety Study of Procaine HCl in HIV-1 Infected Patients” NCT00299338

procaine 25 mg/g + lidocaine 25 mg/g (Emla 5% cream)” NCT06425978

NCT03838068

NCT02726620

NCT06717724

NCT02735317

Known as Anestil ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Enpro ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Gero ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Jenacaine ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Medaject ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Naucaine ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Neocaine ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Novocain ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as NSC-169497 ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as NSC-757280 ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Omnicain ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Pasconeural n ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Planocaine ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Procaina ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Procaine hcl ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as PROCAINE HYDROCHLORIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Procaine hydrochloride component of achromycin ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Procaine hydrochloride component of cardioplegin ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Procaini hydrochloridum ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Rocain ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as Solution of novocain ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Known as SP01A ClinicalTrials.gov intervention name — accepted as the source's own label NCT00113412
1

NCT00299897

Known as Syntocain ChEMBL registry synonym — accepted as the source's own label CHEMBL569
Modality Small molecule CHEMBL569