Drugs / RBS2418

Trials 2 · a red edge is where a trial was stopped

20232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05270213 Jul 2022 → Apr 2027 expected cancer of unknown primary site Riboscience, LLC. Recruiting No outcome recorded
Phase not stated1 trial
NCT05683470 Riboscience, LLC. No longer available No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT07175441 Comparator Apr 2026 → Apr 2027 expected hepatocellular carcinoma Riboscience, LLC. Recruiting No outcome recorded
Phase 2 NCT06824064 Comparator Jan 2025 → Dec 2027 expected colorectal cancer, metastatic malignant neoplasm in the colon Riboscience, LLC. Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as RBS2418 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05270213
3

NCT06824064

NCT05683470

NCT07175441

Action Inhibit “RBS2418 is a potent and selective small molecule inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1).” NCT05270213
Modality Small molecule “RBS2418 is a potent and selective small molecule inhibitor” NCT05270213
Route Oral “RBS2418 will be administered orally” NCT05683470
Target ENPP1 “inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1)” NCT05270213