Drugs / lometrexol
last change Feb 2002 re-read 3 minutes ago

lometrexol

Small molecule

Developed for
lung cancer
Investigated by
Jonsson Comprehensive Cancer Center · National Cancer Institute (NCI) · Tularik

Trials 2

200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00024310 Sep 2001 → ? poisoning Jonsson Comprehensive Cancer Center Unknown No outcome recorded
Phase 21 trial
Phase 2 NCT00033722 Feb 2002 → ? lung cancer Tularik Unknown No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as lometrexol ClinicalTrials.gov intervention name — accepted as the source's own label NCT00033722 ↗
1

NCT00024310 ↗

Known as LOMETREXOL SODIUM ChEMBL registry synonym — accepted as the source's own label CHEMBL34412 ↗
Known as LY-264618 DISODIUM ChEMBL registry synonym — accepted as the source's own label CHEMBL34412 ↗
Known as LY264618 ChEMBL registry synonym — accepted as the source's own label CHEMBL34412 ↗
Known as NSC-722969 ChEMBL registry synonym — accepted as the source's own label CHEMBL34412 ↗
Action Inhibit “Lometrexol may stop the growth of tumors by blocking one of the enzymes necessary for cancer cell growth.” NCT00024310 ↗
Modality Small molecule — CHEMBL34412 ↗
Route Intravenous “Patients receive lometrexol IV over 30-60 seconds immediately followed by paclitaxel IV over 3 hours on day 1.” NCT00024310 ↗