Drugs / Immunoregulatory Dendritic Cells
last change Feb 2024 re-read 3 minutes ago

Immunoregulatory Dendritic Cells

Cell therapy targets CD40 via inhibition

Developed for
type 1 diabetes mellitus
Investigated by
DiaVacs, Inc. · Stanford University · University of Miami · University of Pittsburgh Medical Center · West Penn Allegheny Health System

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02354911 Oct 2015 → Feb 2024 type 1 diabetes mellitus DiaVacs, Inc. Withdrawn No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Immunoregulatory Dendritic Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT02354911 ↗
Action Inhibit “antisense DNA oligonucleotides targeting the primary transcripts of CD40, CD80 and CD86” NCT02354911 ↗
Modality Cell therapy “Autologous dendritic cells harvested by leukapheresis and engineered ex vivo” NCT02354911 ↗
Route Other “administered via blinded intradermal injection” NCT02354911 ↗
Target CD40 “antisense DNA oligonucleotides targeting the primary transcripts of CD40” NCT02354911 ↗