Drugs / TP-0184
last change Apr 2021 re-read 3 minutes ago

TP-0184

targets ACRV1, ACVR1 via inhibition

Developed for
cancer · myelodysplastic syndrome
Investigated by
Sumitomo Pharma America, Inc.

Trials 2

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03429218 Jul 2018 → Mar 2021 cancer Sumitomo Pharma America, Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT04623996 Dec 2020 → Apr 2021 myelodysplastic syndrome Sumitomo Pharma America, Inc. Terminated No outcome recorded Stop: Enrollment

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as TP-0184 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03429218 ↗
1

NCT04623996 ↗

Action Inhibit “TP-0184 is a potent inhibitor of ALK2 or ACRV1 kinase” NCT03429218 ↗
Route Oral “Weekly dose of TP-0184 by oral administration” NCT03429218 ↗
Target ACRV1 “TP-0184 is a potent inhibitor of ALK2 or ACRV1 kinase” NCT03429218 ↗
Target ALK2 “TP-0184 is a potent inhibitor of ALK2 or ACRV1 kinase” NCT03429218 ↗