Drugs / all-trans retinoic acid (ATRA)
last change Oct 2022 re-read 3 minutes ago

all-trans retinoic acid (ATRA)

also known as ATRA

targets CD38, CD55, CD59

Developed for
plasma cell myeloma
Investigated by
Amsterdam UMC, location VUmc · Erasmus Medical Center · UMC Utrecht · University of Turin, Italy · Vejle Hospital

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT02751255 Jul 2016 → Oct 2022 plasma cell myeloma Amsterdam UMC, location VUmc Completed Missed primary

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as all-trans retinoic acid (ATRA) ClinicalTrials.gov intervention name — accepted as the source's own label NCT02751255 ↗
Known as ATRA “all-trans retinoic acid (ATRA)” NCT02751255 ↗
Route Oral “ATRA will be administered twice daily as an oral formulation” NCT02751255 ↗
Target CD38 “ATRA upregulates CD38 levels and downregulates CD55/CD59 levels on MM cells” NCT02751255 ↗
Target CD55 “ATRA upregulates CD38 levels and downregulates CD55/CD59 levels on MM cells” NCT02751255 ↗
Target CD59 “ATRA upregulates CD38 levels and downregulates CD55/CD59 levels on MM cells” NCT02751255 ↗