Drugs / CC-90002
last change Jul 2021 re-read 3 minutes ago

CC-90002

Monoclonal antibody targets CD47 via inhibition

Developed for
acute myeloid leukemia · hematopoietic and lymphoid cell neoplasm · myelodysplastic syndrome
Investigated by
Celgene Corporation

Trials 2

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02641002 Mar 2016 → Jul 2018 acute myeloid leukemia, myelodysplastic syndrome Celgene Corporation Terminated No outcome recorded
Phase 1 NCT02367196 Mar 2015 → Dec 2020 hematopoietic and lymphoid cell neoplasm Celgene Corporation Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as CC-90002 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02641002 ↗
1

NCT02367196 ↗

Action Inhibit “high-affinity binding to CD47 and inhibition of the CD47-SIRPα interaction” PMID 34247273 ↗ Jul 2021
Modality Monoclonal antibody “a humanized anti-CD47 antibody” PMID 34247273 ↗ Jul 2021
Route Intravenous “CC-90002, administered by intravenous (IV) infusion” NCT02367196 ↗
Target CD47 “high-affinity binding to CD47 and inhibition of the CD47-SIRPα interaction” PMID 34247273 ↗ Jul 2021